What a difference a day can make, apparently. Just 24 hours after Pandora unveiled a new tablet design for its Internet radio app, it's flipped the switch on Chromecast support. The sharing icon (which I swear wasn't there yesterday when I was kind of going off on a rant) is now live, and it connects as you'd expect to Chromecast.
Earlier this month, Hulu Plus joined the ranks as the other third-party member of the Chromecast streaming community.
It may seem slightly old-fashioned to the OJ generation, but British journalists have been campaigning for more than a decade to bring TV news cameras into courtrooms. Today they got a breakthrough: the UK's Ministry of Justice has partially lifted its ban on filming in a total of five courtrooms in ...
You might see more (good) phones and tablets with Intel inside, now that the company has started shipping its new LTE-capable XMM 7160 chip to manufacturers. We say "new," but it's actually been a long time coming -- the company first revealed the radio in early 2012 and officially announced it in ...
Results of the CHILL-MI trial presented at TCT 2013
PUBLIC RELEASE DATE:
30-Oct-2013
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Contact: Judy Romero jromero@crf.org Cardiovascular Research Foundation
Therapeutic hypothermia is safe and feasible as adjunctive care for heart attack patients
SAN FRANCISCO, CA OCTOBER 30, 2013 A clinical trial shows that rapidly cooling patients who have suffered ST-elevation myocardial infarction (STEMI, the most serious form of a heart attack) prior to restoring blood flow is safe and feasible. The findings of the CHILL-MI trial were presented today at the 25th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.
CHILL-MI was a prospective, randomized multicenter efficacy trial that builds on initial findings from the pilot RAPID MI-ICE trial, which showed significantly reduced infarct size when patients were cooled below 35C before angioplasty. The primary endpoint for CHILL-MI was myocardial infarct size as a percentage of myocardium at risk, assessed by magnetic resonance imaging (MRI) at 2-6 days after the procedure.
This study enrolled 120 patients in nine centers with large anterior and inferior STEMIs with infarct duration of less than six hours. Patients underwent PCI and were randomized to the traditional standard of care or hypothermia induced by rapid infusion of up to 2,000 ml cold saline combined with endovascular cooling. In the hypothermia group, cooling was initiated before PCI and continued for one hour after reperfusion with a target temperature of 33C followed by spontaneous rewarming.
Due to the time required for cooling, door-to-balloon time was impacted by an average of nine minutes in the hypothermia group. The primary endpoint, infarct size in relation to the area at risk was non-significantly reduced by 13 percent (p=0.15) with similar myocardium at risk between both groups. Although the trial missed its primary endpoint, exploratory analysis indicates an effect in the early anterior patient population with a 33 percent reduction of infarct size.
At 4515 days there was no mortality. However, the incidence of clinical heart failure was 14 percent in the control group and 3 percent in the hypothermia group (p
"Hypothermia using intravenous cold saline and an endovascular venous cooling catheter was safe, feasible and reduced temperature to 34.7C before reperfusion, with a delay of reperfusion of nine minutes," said lead investigator David Erlinge, MD. Dr. Erlinge is a Professor in the Department of Cardiology at Lund University and Skane University Hospital in Sweden.
"Although reduction in infarct size in relation to area at risk did not reach significance, we found a significant reduction in the incidence of clinical heart failure. Furthermore, we observed a large reduction in infarct size in the anterior patient population, but this needs to be validated in a prospective study."
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The CHILL-MI trial was funded by Philips. Dr. Erlinge reported a speaker's honoraria from Philips.
About CRF and TCT
The Cardiovascular Research Foundation (CRF) is an independent, academically focused nonprofit organization dedicated to improving the survival and quality of life for people with cardiovascular disease through research and education. Since its inception in 1991, CRF has played a major role in realizing dramatic improvements in the lives of countless numbers of patients by establishing the safe use of new technologies and therapies in interventional cardiovascular medicine. CRF is the sponsor of the Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Celebrating its 25th anniversary this year, TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine. For more information, visit http://www.crf.org and http://www.tctconference.com.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Results of the CHILL-MI trial presented at TCT 2013
PUBLIC RELEASE DATE:
30-Oct-2013
[
| E-mail
]
Share
Contact: Judy Romero jromero@crf.org Cardiovascular Research Foundation
Therapeutic hypothermia is safe and feasible as adjunctive care for heart attack patients
SAN FRANCISCO, CA OCTOBER 30, 2013 A clinical trial shows that rapidly cooling patients who have suffered ST-elevation myocardial infarction (STEMI, the most serious form of a heart attack) prior to restoring blood flow is safe and feasible. The findings of the CHILL-MI trial were presented today at the 25th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.
CHILL-MI was a prospective, randomized multicenter efficacy trial that builds on initial findings from the pilot RAPID MI-ICE trial, which showed significantly reduced infarct size when patients were cooled below 35C before angioplasty. The primary endpoint for CHILL-MI was myocardial infarct size as a percentage of myocardium at risk, assessed by magnetic resonance imaging (MRI) at 2-6 days after the procedure.
This study enrolled 120 patients in nine centers with large anterior and inferior STEMIs with infarct duration of less than six hours. Patients underwent PCI and were randomized to the traditional standard of care or hypothermia induced by rapid infusion of up to 2,000 ml cold saline combined with endovascular cooling. In the hypothermia group, cooling was initiated before PCI and continued for one hour after reperfusion with a target temperature of 33C followed by spontaneous rewarming.
Due to the time required for cooling, door-to-balloon time was impacted by an average of nine minutes in the hypothermia group. The primary endpoint, infarct size in relation to the area at risk was non-significantly reduced by 13 percent (p=0.15) with similar myocardium at risk between both groups. Although the trial missed its primary endpoint, exploratory analysis indicates an effect in the early anterior patient population with a 33 percent reduction of infarct size.
At 4515 days there was no mortality. However, the incidence of clinical heart failure was 14 percent in the control group and 3 percent in the hypothermia group (p
"Hypothermia using intravenous cold saline and an endovascular venous cooling catheter was safe, feasible and reduced temperature to 34.7C before reperfusion, with a delay of reperfusion of nine minutes," said lead investigator David Erlinge, MD. Dr. Erlinge is a Professor in the Department of Cardiology at Lund University and Skane University Hospital in Sweden.
"Although reduction in infarct size in relation to area at risk did not reach significance, we found a significant reduction in the incidence of clinical heart failure. Furthermore, we observed a large reduction in infarct size in the anterior patient population, but this needs to be validated in a prospective study."
###
The CHILL-MI trial was funded by Philips. Dr. Erlinge reported a speaker's honoraria from Philips.
About CRF and TCT
The Cardiovascular Research Foundation (CRF) is an independent, academically focused nonprofit organization dedicated to improving the survival and quality of life for people with cardiovascular disease through research and education. Since its inception in 1991, CRF has played a major role in realizing dramatic improvements in the lives of countless numbers of patients by establishing the safe use of new technologies and therapies in interventional cardiovascular medicine. CRF is the sponsor of the Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Celebrating its 25th anniversary this year, TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine. For more information, visit http://www.crf.org and http://www.tctconference.com.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Jack Osbourne may have been speaking for all the contestants of Dancing with the Stars, Week 7, when he complained about feeling tired. "I think I have a little of the midseason blues," he said, early in the show. "The dances are longer, and now we have two dances. It's pretty heavy." In the rehearsal footage, Elizabeth Berkley fought with her partner, Val Chmerkovskiy; Amber Riley and Derek Hough both groaned from the pain of injuries; and Snooki proclaimed, "My brain feels like scrambled eggs."
VENICE, Italy (AP) — An Italian company that built Coney Island's latest attractions and an amusement park in a never-activated nuclear plant in Germany has unveiled plans to invest 80 million euros ($110 million) for a theme park in Venice.
Alberto Zamperla, one of the main investors, said Wednesday the theme park is planned for an abandoned island that once housed an incinerator, bringing economic and environmental benefits by cleaning up a toxic site and creating 500 jobs.
The project envisions a 55-meter (yard)-tall Ferris wheel, a roller coaster and other rides, alongside installations illustrating the Venetian lagoon's fragile ecology and the city's history.
Zamperla is loath to call it an amusement park — an easy target for detractors in Venice — and the plan still faces a series of approvals.
Don't be fooled by the bright, jovial colors of this satellite image, because it's hiding a darker truth: the world is being wrenched apart at its seams.
It may seem slightly old-fashioned to the OJ generation, but British journalists have been campaigning for more than a decade to bring TV news cameras into courtrooms. Today they got a breakthrough: the UK's Ministry of Justice has partially lifted its ban on filming in a total of five courtrooms in ...
You might see more (good) phones and tablets with Intel inside, now that the company has started shipping its new LTE-capable XMM 7160 chip to manufacturers. We say "new," but it's actually been a long time coming -- the company first revealed the radio in early 2012 and officially announced it in ...![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
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